In the last issue of The Week in Chiropractic (March 4, 2002) An op-ed piece in TIME.com, written by Leon Jaroff, was discussed. Anthony L. Rosner, Ph.D., FCER's Director of Research, sent the following response to Mr. Jaroff. For a copy of the complete article by Dr. Rosner (with references), please e-mail a request to FCERedit@aol.com. Dear Mr. Jaroff: Once in a while a truly ill-conceived, misleading, ignorant and offensive article taints what the reader hopes to be an informative press. I regret to have come to the conclusion that your recent submission, "Back Off, Chiropractors!" fits every one of those criteria. I am dismayed that a person of your background and stature has failed one of the primary tenets of research, which is of course to conduct a thorough review of available information which has actually appeared in the refereed scientific literature for the past 20 years. The article I have enclosed for your reference which just appeared in the Annals of Internal Medicine is one of many summaries of the current evidence which your article has chosen to ignore. To begin, you will notice that not all neurologists would share the opinions you have drawn upon so liberally in your article-as one of the authors of the enclosed reprint is in fact a leading neurologist who for decades has published articles in the peer-reviewed journals offering data in support of many of the basic tenets of chiropractic theory. I would first like to acquaint you with some of the basic information regarding chiropractic and then discuss some of the most troubling aspects of your article. In the interests of both objective reporting and the sharing of credible information in an open press, I hope that you will be able to respond appropriately to this material. General Comments: Chiropractic is recognized and licensed in every state and province in North America, as well as in 76 nations representing the European, Asian, Latin American, Caribbean, Eastern Mediterranean, and Pacific domains.2 The increasing acceptance of chiropractic as a legitimate health care profession has occurred in part through the increasing emphasis on research by professional organizations and the colleges with funding by outside agencies. It also stems from the accrediting and review of educational curricula at chiropractic colleges around the world, 16 of which are accredited in the United States by the Council for Chiropractic Education (CCE). The CCE has had accrediting agency status with the U.S. Department of Education since 1974 and with the Council on Postsecondary Accreditation since 1976. The minimum content of hours required for CCE accreditation is 4,200 and ranges from 4,400 to 5,220 hours at colleges nationwide. In fact, the didactic basic science and clinical science hours among chiropractic colleges around the United States compares extremely closely with the corresponding averages obtained from medical schools nationwide. With over 65,000 licensed practitioners in the United States, chiropractic has taken its place as the foremost profession through which spinal manipulations have been administered-largely in the treatment of back pain but increasingly for other disorders such as neck pain; headache; cumulative trauma disorders in the extremities; infantile colic; enuresis; otitis media; asthma; and GI dysfunctions (these will be cited below). Indeed, it has been estimated that the total number of chiropractic office visits nationwide each year is 250 million, with 94% of all spinal manipulations administered by chiropractors. What may not as well-known as it should is that the practice of chiropractic includes a complete physical examination and establishing a diagnosis. The aim is to establish biomechanical and neurological integrity through an assortment of noninvasive measures, many (but not all) of which are manual. These would include manipulation, mobilization, soft-tissue and non-force techniques, exercise and rehabilitation, and occasionally such educational programs as nutritional counseling or wellness care. With regards to back pain, the efficacy of these procedures has been reviewed repeatedly by carefully structured guidelines, developed both within the profession and by multidisciplinary panels representing the U.S. and no less than 10 other countries worldwide. According to Meeker and Haldeman, 73 randomized clinical trials comparing spinal manipulation with either placebos or other treatments in the management of back pain have been published in the scientific literature-almost all within the past 20 years. Meta-analyses addressing acute low-back pain have also appeared in the literature, supporting the appropriateness of spinal manipulation in managing acute low-back pain. According to a systematic review by van Tulder, "There is limited evidence that manipulation is more effective than a placebo treatment." Although contradictory results did not allow van Tulder to compare manipulation to other physiotherapeutic applications, there was no such uncertainty regarding chronic low-back pain. Here van Tulder unequivocally states that "There is strong evidence that manipulation is more effective than a placebo treatment.... There is moderate evidence that manipulation is more effective for chronic LBP than usual care by the general practitioner, bed-rest, analgesics, and massage." Specific Concerns: The opportunism in your article is hard to disguise. The consistently derogatory language used to describe chiropractic ("bewildering... weird... troublesome... damning... bizarre") can only be taken to reveal the overriding sentiments of the author and does little to enlighten. Your communication comes on the heels of a sensationalist banner headline (printed in type larger than that used by the New York Times that gave the first descriptions of the September 11 terrorist attacks in New York and Washington) which warned of the "perils" of chiropractic in the Canadian National Post, based primarily upon two highly flawed studies by neurologists which were at odds with the vast preponderance of literature appearing in the scientific journals. It delves into a journal almost never quoted previously in the national media in order to ferret out an article which was critical of the language used in some patient brochures from some chiropractic organizations - conspicuously omitting any reference to the vast majority of other published studies in that very same journal which for over a quarter of a century have indicated that chiropractic treatments not only match the medical alternatives for treating such diverse conditions as back pain, carpal tunnel syndrome, cervicogenic, migraine and tension-type headache, dysmenorrhea, premenstrual syndrome, infantile colic, enuresis, and even ear infections, but do so for longer durations after treatment and without the common, injurious or even fatal side of medications. These "side effects" need to be scrutinized more closely: - A review of over half a dozen peer-reviewed published scientific papers puts the risk of cerebrovascular accidents (including stroke) associated with spinal manipulation at anywhere from 1 per 400,000 to 1 per 5.85M cervical manipulations, the latter figure representing the most rigorously derived frequency. On the other hand, the risk of deaths from the use of such medicines as nonsteroidal antiinflammatory agents (NSAIDs) or from surgery to treat many of the same conditions as those managed by chiropractors is 400 to 700 times greater; yet warnings pertaining to the use of these particular options do not seem to have been mentioned by your commentary. - Death rates due to medication side effects have been estimated by the Institute of Medicine to range from 230,000-280,000 per year. Those caused by commonly used NSAIDs (such as ibuprofen) have been reported to approach an annual rate of 16,000-dwarfing any estimates of chiropractic fatalities by several orders of magnitude. - As many as 68 everyday activities have been shown to disrupt cerebral circulation, 18 of which have actually been associated with vascular accidents but are decidedly non-manipulative. Such activities would include childbirth; interventions by surgeons or anesthetists during surgery; calisthenics; yoga; turning the head while driving a vehicle, undergoing x-rays, or treating a bleeding nose; star gazing; swimming; rap dancing; and beauty parlor events. - Experiments with arterial models at the University of Calgary have shown that peak elongations of the vertebral artery during neck manipulations are at most 11% of the elongations that would be seen at the arterial failure limits; in fact, these elongations are consistently lower than those seen during routine diagnostic tests. - The common musculoskeletal conditions routinely diagnosed and treated by chiropractors were shown in one study to have eluded first-year medical orthopedic residents, who failed a validated competency examination. The chiropractic profession remains deeply concerned about and is actively researching the occurrences of any cerebrovascular accidents ever to occur with manipulations, which remains an event rarer than most activities in daily life. What is already becoming more and more apparent is that vertebral artery failures need to be regarded as the result of cumulative events such as those I have mentioned above rather than simply the recent visits to the chiropractor as maintained by the study which you mentioned. The only constructive alternative would be to continue to pursue productive research, hopefully with cooperation between the chiropractic and medical professions. That goal is obviously discouraged by your commentary. The facts that randomized clinical trials support both the efficacy and safety of chiropractic treatment not only for managing back pain but for headaches, carpal tunnel syndrome, infantile colic and bedwetting problems as well should be shared with your audience as well if they are to be given truly meaningful medical advice on treatment options, the centerpiece of which should quite simply be the risk-to-benefit ratio. Guidelines of no less than 11 nations have recognized the effectiveness of chiropractic as a viable treatment option for millions of patients. Until this type of information can be freely shared with your audience as well, they are being seriously misled by the one-sided presentation on your Web site. As the Director of Research in a National Foundation which for over 50 years has supported research and postgraduate support in areas pertaining to chiropractic healthcare, I am horrified by the grossly misleading impression that your recent Web site commentary has created. Because your audience should be entitled to the best available healthcare information, I hope that it will be possible for you to incorporate the issues I have raised in another of your commentaries in the near future.