10/22/2001 http://www.usatoday.com/news/healthscience/health/2001-10- 23-kids-drugs.htm Kids get psychiatric drugs too often By Marilyn Elias, USA TODAY Doctors are increasingly prescribing psychiatric drugs such as Ritalin and Prozac to preschoolers, despite questions about safety and effectiveness, experts reported over the weekend. "Every pressure I'm aware of is pushing toward more use of these pills in young kids, and the potential for problems is huge," says child psychiatrist Glen Elliott of the University of California Medical School in San Francisco. He spoke at the American Academy of Pediatrics meeting in San Francisco. HMOs are encouraging quick diagnoses, working parents often can't be home to enforce structured behavior-improvement programs, and everyone seems to want "quick fixes," Elliott says. Nobody knows exactly how many preschool children are on psychiatric drugs. Some evidence suggests it's only a few out of every 100 youngsters. But concern has been mounting since a report last year showed that Ritalin use more than tripled in preschoolers between 1991 and 1995, and prescriptions for antidepressants doubled in that age group during the same period. Newer, comprehensive figures are not available. There are a handful of scientifically sound studies confirming Ritalin's effectiveness in 4- and 5-year-olds, says Marsha Rappley, a pediatrician at Michigan State University's College of Human Medicine in East Lansing. Side effects range from mild to significant ­ headaches, stomachaches, sleep problems and loss of appetite. But there is very little research on safety and effectiveness in kids under 4. Her own recent study of Michigan children 3 and younger diagnosed with attention deficit/hyperactivity disorder found a pattern of multidrug use: About a third of those treated were taking two or three psychiatric drugs. Mental health services were sparse, "so we may be ignoring their core problems and setting the stage for spotty treatment for the rest of their lives," Rappley says. Elliott worries about the long-term dangers of prescribing drugs such as Prozac to small children. Antidepressants change how brain chemicals work, and permanent changes might result from kids taking such drugs "since we know a lot of brain development is still going on at this young age," he says. "To fantasize (that the drugs) can't have adverse consequences is a big leap. So far, we've not seen any. But we're not very sophisticated at knowing what to look for. There are going to be unanticipated effects from such powerful medications," Elliott says. Parents concerned about preschoolers' behavior problems should check with their public schools, Rappley suggests. State and federal governments co-fund early treatment programs that may offer the best hope for heading off serious emotional problems and avoiding use of psychiatric drugs, she says.