USA Today, Thursday, July 5, 2001 Doctors step out; drug salespeople step in By Ivan Oransky Reprinted with permission of the author Imagine it's late at night. You've been feeling blue for a while. You turn on the TV, and someone depressed appears on the screen. Soothing music is accompanied by the name of a popular antidepressant. "Speak to your doctor," intones a voice-over, as the formerly depressed patient appears again, this time smiling and playing with his daughter. The ad seems to be made for you. So you make an appointment to see your doctor, who, seeing that you're depressed, prescribes the drug you saw on TV ­ after you suggest it during your 5-minute visit. Sounds great. A patient was educated and empowered to get the drug he needed. The only problem: You actually suffer from bipolar disorder ­ formerly known as manic depression ­ and the antidepressants you thought would help you will only throw you into a mania, placing you at real risk of committing reckless behavior. Your doctor didn't ask the right questions. He didn't ask about a past history of mania or members of your family who had the disease. Depression ­ which you're undoubtedly suffering from ­ is actually just half of your illness. The scenario sounds scary. And it is. But who's to blame? The ad that sent you to the doctor or the doctor for not making the right diagnosis? Direct-to-consumer drug advertising, on which drug companies spent $1.8 billion in 1999, is growing, with substantial results. A 1997 survey found that more than a third of patients had asked their doctors about drugs they saw in ads, and nearly a quarter of patients had asked for a prescription for the drugs the ads promoted. Proponents of the ads say that they help educate patients about diseases they may not know they have, or about better ways to treat their known illnesses. Citing actions by the Food and Drug Administration (FDA) to curb certain ads, critics say many ads understate risks and side effects or oversell what drugs are meant for. More troubling, however, is the segment of doctors who won't "just say no" when patients ask them for drugs. In the 1997 survey, three- quarters of patients who asked for a specific drug left their doctors' offices with a prescription for that drug. Some doctors think that if they make a clinical decision that a patient doesn't need a drug they ask for, they'll lose credibility in the eyes of patients. "We have a lot of data that suggest that physicians having those office experiences do roll over and prescribe the drug that's requested," says Steven Findlay, director of research at the National Institute for Health Care Management. Direct-to-consumer advertising has become part of our pill culture. That makes it difficult for doctors to control their relationship with patients, particularly demanding ones. Some groups are understandably concerned about these trends. At its June annual meeting, the American Medical Association (AMA) considered but failed to approve a resolution that would urge the government to ban direct-to-consumer drug ads from television, newspapers and magazines. Banning the ads, which already are regulated by the FDA, isn't a great solution, even forgetting that it cuts close to a violation of the First Amendment. The proposal made at the AMA meeting would have only sidestepped the real issue, which is that too many doctors can't or won't spend the time necessary to make a correct diagnosis. Pressured by a ticking managed-care clock, doctors take the quick way out. If it looks like a duck and walks like a duck, it must be a duck. Who wants to argue with patients? If you're sneezing and it's May, you must need the antihistamine you saw on TV. If you have a fever and a cough, you must need antibiotics, even if that sort of practice gives rise to superbacteria that can't be killed by any antibiotics in our arsenal, as we're learning. Many times, that logic will hold and is perfectly safe. But if you look like a patient with depression, and you're actually a patient with bipolar disorder, you'd best hope that your doctor doesn't prescribe an antidepressant without asking the right questions first. Doctors need to stand firm and do what's right in the long term clinically for their patients, not what's right in the immediate term to avoid angering the demanding ones. The buck stops here, where the pen hits the prescription pad. Ivan Oransky, M.D., is editor of Praxis Post, an online medical magazine.